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Anastrozole is the active compound in Arimidex, originally developed to treat breast cancer in post-menopausal women. It belongs to a class of drugs called aromatase inhibitors. In fitness and performance circles, it's widely used to keep oestrogen levels in check during steroid cycles.
| Active Ingredient | Anastrozole |
| Half-life | 40–50 hours |
| Form | Oral tablet |
| Dose (Men) | 0.5–1mg every other day |
| Dose (Women) | Not recommended for performance use |
| Detection Time | Approx. 2 weeks |
| Anabolic Rating | N/A |
| Androgenic Rating | N/A |
Anastrozole blocks the aromatase enzyme, which is responsible for converting testosterone into oestrogen. Less aromatase activity means lower oestrogen levels in the body. This helps prevent oestrogen-related side effects that can occur when using anabolic steroids.
Users typically notice reduced water retention and a leaner, drier appearance within the first week of use. Mood and energy can also stabilise when oestrogen is kept at a healthy level rather than being completely suppressed. It works best when used reactively or as a preventative measure alongside aromatising compounds.
Anastrozole is typically run alongside aromatising steroids such as testosterone, starting at 0.5mg every other day and adjusting based on bloodwork. It is not needed during post-cycle therapy and should be tapered off as the steroid cycle ends. Blood tests are the best way to dial in the right dose and avoid crashing oestrogen too low.
Keep at room temperature (15–25°C), away from light and moisture. Leave in the original packaging.
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